| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60367.1 | AEJ60368.1 | Spith_0080 | Spith_0081 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | Glycosidase related protein; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family. | 0.523 |
| AEJ60367.1 | AEJ60369.1 | Spith_0080 | Spith_0082 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man). | 0.530 |
| AEJ60367.1 | AEJ60516.1 | Spith_0080 | Spith_0230 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR004089; KEGG: sta:STHERM_c02460 transcriptional regulatory protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Periplasmic binding protein/LacI transcriptional regulator; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer. | 0.635 |
| AEJ60367.1 | AEJ60542.1 | Spith_0080 | Spith_0256 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS. | 0.772 |
| AEJ60367.1 | AEJ61321.1 | Spith_0080 | Spith_1049 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit. | 0.680 |
| AEJ60367.1 | AEJ62498.1 | Spith_0080 | Spith_2243 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein. | 0.545 |
| AEJ60367.1 | ribBA | Spith_0080 | Spith_0467 | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.429 |
| AEJ60368.1 | AEJ60367.1 | Spith_0081 | Spith_0080 | Glycosidase related protein; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family. | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | 0.523 |
| AEJ60368.1 | AEJ60369.1 | Spith_0081 | Spith_0082 | Glycosidase related protein; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family. | N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man). | 0.950 |
| AEJ60369.1 | AEJ60367.1 | Spith_0082 | Spith_0080 | N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man). | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | 0.530 |
| AEJ60369.1 | AEJ60368.1 | Spith_0082 | Spith_0081 | N-acylglucosamine 2-epimerase; Catalyzes the reversible epimerization of cellobiose to 4-O- beta-D-glucopyranosyl-D-mannose (Glc-Man). | Glycosidase related protein; Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose; Belongs to the glycosyl hydrolase 130 family. | 0.950 |
| AEJ60516.1 | AEJ60367.1 | Spith_0230 | Spith_0080 | PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR004089; KEGG: sta:STHERM_c02460 transcriptional regulatory protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Periplasmic binding protein/LacI transcriptional regulator; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer. | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | 0.635 |
| AEJ60516.1 | AEJ61321.1 | Spith_0230 | Spith_1049 | PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR004089; KEGG: sta:STHERM_c02460 transcriptional regulatory protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Periplasmic binding protein/LacI transcriptional regulator; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer. | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit. | 0.690 |
| AEJ60516.1 | AEJ62498.1 | Spith_0230 | Spith_2243 | PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR004089; KEGG: sta:STHERM_c02460 transcriptional regulatory protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Periplasmic binding protein/LacI transcriptional regulator; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer. | Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein. | 0.545 |
| AEJ60516.1 | ribBA | Spith_0230 | Spith_0467 | PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR004089; KEGG: sta:STHERM_c02460 transcriptional regulatory protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Periplasmic binding protein/LacI transcriptional regulator; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.440 |
| AEJ60542.1 | AEJ60367.1 | Spith_0256 | Spith_0080 | PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS. | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | 0.772 |
| AEJ60542.1 | AEJ61321.1 | Spith_0256 | Spith_1049 | PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS. | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit. | 0.690 |
| AEJ60542.1 | AEJ62498.1 | Spith_0256 | Spith_2243 | PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS. | Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein. | 0.545 |
| AEJ60542.1 | ribBA | Spith_0256 | Spith_0467 | PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS. | GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.440 |
| AEJ61321.1 | AEJ60367.1 | Spith_1049 | Spith_0080 | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit. | PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sta:STHERM_c00930 HTH-type transcriptional regulator CelR; PFAM: HTH transcriptional regulator, LacI; Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. | 0.680 |