STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60378.1KEGG: sta:STHERM_c01040 hypothetical protein; SPTR: Putative uncharacterized protein. (226 aa)    
Predicted Functional Partners:
AEJ60377.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: sta:STHERM_c01030 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimer [...]
       0.705
AEJ60376.1
PFAM: Nucleotidyl transferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835; KEGG: sta:STHERM_c01020 hypothetical protein; PFAM: Nucleotidyl transferase; SPTR: UDP-glucose pyrophosphorylase.
       0.491
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.