STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEJ60393.1PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: sta:STHERM_c01180 hypothetical protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein. (173 aa)    
Predicted Functional Partners:
AEJ60391.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR004105:IPR003594:IPR002545; KEGG: sta:STHERM_c01160 hypothetical protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup, homodimeric; CheW-like protein; SMART: ATP-binding region, ATPase-like; Signal [...]
 
 0.998
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.992
AEJ62053.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR010808:IPR 004105; KEGG: sta:STHERM_c17230 chemotaxis protein CheA; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, P2 response regulator-binding; Signal [...]
 
 0.992
AEJ60394.1
Hypothetical protein; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; KEGG: sta:STHERM_c01190 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 0.975
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.973
AEJ60395.1
MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: sta:STHERM_c01200 chemotaxis protein methyltransferase; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type.
 
  
 0.972
AEJ60387.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; TIGRFAM: X-X-X-Leu-X-X-Gly heptad repeats; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013163:IPR004089; KEGG: sta:STHERM_c01130 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache, type 2; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor.
 
 0.971
AEJ60388.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; TIGRFAM: X-X-X-Leu-X-X-Gly heptad repeats; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013163:IPR004089; KEGG: sta:STHERM_c01130 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache, type 2; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor.
 
 0.971
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.968
AEJ60491.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013163:IPR004089; KEGG: sta:STHERM_c02210 chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache, type 2; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor.
 
 0.966
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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