STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60407.1Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sta:STHERM_c01320 hypothetical protein; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor. (379 aa)    
Predicted Functional Partners:
AEJ62209.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sta:STHERM_c19050 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator.
 
 
 0.996
AEJ62210.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: sta:STHERM_c19060 hypothetical protein; PFAM: Bacterial inner-membrane translocator; SPTR: Amino acid/amide ABC transporter membrane protein 1, HAAT family.
 
 
 0.994
AEJ62208.1
PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19040 branched-chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family.
 
 
 0.992
AEJ62207.1
PFAM: ABC transporter; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c19030 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family.
 
 
 0.988
AEJ62211.1
Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sta:STHERM_c19070 hypothetical protein; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor.
  
  
 
0.925
hisE
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphatase; InterPro IPR008179; KEGG: sta:STHERM_c01310 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase.
  
    0.800
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; InterPro IPR006062; KEGG: sta:STHERM_c01300 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; PFAM: Histidine b [...]
  
    0.791
AEJ60408.1
KEGG: sta:STHERM_c01330 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
 
 0.577
AEJ60409.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
 0.562
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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