STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60408.1KEGG: sta:STHERM_c01330 hypothetical protein; SPTR: Putative uncharacterized protein. (513 aa)    
Predicted Functional Partners:
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; InterPro IPR006062; KEGG: sta:STHERM_c01300 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; PFAM: Histidine b [...]
       0.773
hisE
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphatase; InterPro IPR008179; KEGG: sta:STHERM_c01310 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase.
       0.773
AEJ60407.1
Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sta:STHERM_c01320 hypothetical protein; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor.
       0.773
AEJ60409.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
       0.548
AEJ60403.1
KEGG: sta:STHERM_c01280 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.540
AEJ60404.1
KEGG: sta:STHERM_c01290 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.540
AEJ60402.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: sta:STHERM_c01270 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; Belongs to the thioredoxin family.
       0.487
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.