STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
rsmIRibosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (226 aa)    
Predicted Functional Partners:
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
   
 
 0.714
AEJ60436.1
PFAM: Anti-sigma-28 factor, FlgM; InterPro IPR007412; KEGG: sta:STHERM_c01610 hypothetical protein; PFAM: Anti-sigma-28 factor, FlgM; SPTR: Anti-sigma-28 factor FlgM family protein.
       0.684
AEJ60438.1
tRNA/rRNA methyltransferase (SpoU); PFAM: SpoU rRNA Methylase family; COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: sta:STHERM_c01630 RNA methyltransferase, TrmH family; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: tRNA/rRNA methyltransferase (SpoU).
     
 0.672
AEJ60434.1
KEGG: sta:STHERM_c01590 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.627
AEJ60437.1
PFAM: Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: sta:STHERM_c01620 hypothetical protein; PFAM: Alcohol dehydrogenase, iron-type; SPTR: Iron-containing alcohol dehydrogenase.
       0.613
AEJ60433.1
PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: sta:STHERM_c01580 cation efflux family protein; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein.
       0.583
AEJ60888.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
   0.477
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.476
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.454
AEJ62026.1
(Uracil-5)-methyltransferase; PFAM: tRNA (Uracil-5-)-methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: sta:STHERM_c16950 hypothetical protein; PFAM: (Uracil-5)-methyltransferase; SPTR: (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
 
  
 0.441
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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