Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60439.1PFAM: OsmC-like protein; COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: sta:STHERM_c01640 hypothetical protein; PFAM: Peroxiredoxin, OsmC-like protein; SPTR: Putative uncharacterized protein. (138 aa)    
Predicted Functional Partners:
AEJ60440.1
PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein, YruB-family; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109:IPR011911; KEGG: sta:STHERM_c01650 hypothetical protein; PFAM: Glutaredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: Glutaredoxin-like protein, YruB.
     
 0.791
AEJ60441.1
Metal dependent phosphohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607:IPR006675; KEGG: sta:STHERM_c01660 HD domain-containing protein; PFAM: Metal-dependent hydrolase HDOD; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG.
       0.575
AEJ60442.1
PFAM: Lon protease (S16) C-terminal proteolytic domain; COGs: COG1067 ATP-dependent protease; InterPro IPR008269; KEGG: sta:STHERM_c01670 hypothetical protein; PFAM: Peptidase S16, lon C-terminal; SPTR: Peptidase S16 lon domain protein.
  
    0.489
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.468
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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