STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60441.1Metal dependent phosphohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607:IPR006675; KEGG: sta:STHERM_c01660 HD domain-containing protein; PFAM: Metal-dependent hydrolase HDOD; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG. (497 aa)    
Predicted Functional Partners:
AEJ61659.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
    0.724
AEJ61379.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c10790 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
  
     0.702
AEJ61251.1
Protein serine/threonine phosphatase with extracellular sensor; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: sta:STHERM_c09530 HAMP domain-containing protein; PFAM: Sporulation stage II, protein E C-terminal; HAMP linker domain; SMART: Protein phosphatase 2C-related; HAMP linker domain; SPTR: Protein serine/threonine phosphatase.
 
     0.701
AEJ61022.1
KEGG: sta:STHERM_c14800 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.684
AEJ61658.1
PFAM: FlaG protein; InterPro IPR005186; KEGG: sta:STHERM_c07720 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein.
 
     0.679
AEJ62134.1
Protein of unknown function DUF2225; PFAM: Uncharacterized protein conserved in bacteria (DUF2225); COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: sta:STHERM_c18340 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: Putative uncharacterized protein.
 
     0.668
AEJ62439.1
KEGG: sta:STHERM_c21410 hypothetical protein; SPTR: Putative uncharacterized protein.
  
   
 0.665
AEJ60625.1
KEGG: sta:STHERM_c03720 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.652
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
     0.638
AEJ61723.1
PFAM: Bacterial DNA-binding protein; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: sta:STHERM_c06940 hypothetical protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein.
 
     0.633
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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