STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60443.1PFAM: NUDIX domain; InterPro IPR000086; KEGG: sta:STHERM_c01680 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase. (214 aa)    
Predicted Functional Partners:
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
  
 0.821
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.652
AEJ60442.1
PFAM: Lon protease (S16) C-terminal proteolytic domain; COGs: COG1067 ATP-dependent protease; InterPro IPR008269; KEGG: sta:STHERM_c01670 hypothetical protein; PFAM: Peptidase S16, lon C-terminal; SPTR: Peptidase S16 lon domain protein.
       0.650
AEJ60444.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sta:STHERM_c01690 hypothetical protein; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
       0.569
AEJ61091.1
ATP-dependent RNA helicase RhlB; PFAM: DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; KEGG: sta:STHERM_c14160 ATP-dependent RNA helicase RhlB; SPTR: Putative uncharacterized protein.
  
 0.534
AEJ61988.1
PFAM: DbpA RNA binding domain; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR005580; KEGG: sta:STHERM_c16690 hypothetical protein; PFAM: DbpA, RNA-binding; SPTR: DbpA RNA-binding domain protein.
  
 0.534
AEJ60440.1
PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein, YruB-family; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109:IPR011911; KEGG: sta:STHERM_c01650 hypothetical protein; PFAM: Glutaredoxin; SPTR: Putative uncharacterized protein; TIGRFAM: Glutaredoxin-like protein, YruB.
 
  
 0.461
AEJ60441.1
Metal dependent phosphohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607:IPR006675; KEGG: sta:STHERM_c01660 HD domain-containing protein; PFAM: Metal-dependent hydrolase HDOD; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG.
  
    0.447
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.