STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60444.1PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sta:STHERM_c01690 hypothetical protein; PFAM: Nitroreductase-like; SPTR: Nitroreductase. (175 aa)    
Predicted Functional Partners:
AEJ61881.1
PFAM: Nitroreductase family; COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: shg:Sph21_2015 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase.
  
     0.696
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.608
AEJ60443.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: sta:STHERM_c01680 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
       0.569
AEJ60442.1
PFAM: Lon protease (S16) C-terminal proteolytic domain; COGs: COG1067 ATP-dependent protease; InterPro IPR008269; KEGG: sta:STHERM_c01670 hypothetical protein; PFAM: Peptidase S16, lon C-terminal; SPTR: Peptidase S16 lon domain protein.
       0.483
AEJ61155.1
Abortive infection protein; PFAM: CAAX amino terminal protease family; InterPro IPR003675; KEGG: sta:STHERM_c12770 hypothetical protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein.
  
  
 0.471
AEJ62264.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19580 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.441
AEJ62265.1
PFAM: ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sta:STHERM_c19590 transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.441
AEJ62332.1
PFAM: ABC-2 type transporter; TIGRFAM: ABC-2 type transporter, NodJ family; InterPro IPR013525; KEGG: sta:STHERM_c20340 ABC-type Nod factor export system, permease; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter.
  
  
 0.441
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
     
 0.422
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
  
 0.401
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.