STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60478.1Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c02070 permease involved in lipoprotein release; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein. (417 aa)    
Predicted Functional Partners:
AEJ60480.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c02090 ATP-binding/permease MacB; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.968
AEJ60477.1
KEGG: sta:STHERM_c02060 outer membrane protein involved in lipoprotein sorting; SPTR: Putative uncharacterized protein.
 
 
 
 0.943
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.864
AEJ62541.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c22460 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.860
AEJ61306.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c10090 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Transporter; manually curated.
 
 
 0.858
AEJ60479.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c02080 permease, involved in lipoprotein release; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
    
0.833
AEJ60481.1
PFAM: Bacterial regulatory proteins, tetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: sta:STHERM_c02100 transcriptional activator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family.
 
     0.800
AEJ60476.1
KEGG: sta:STHERM_c02050 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.772
AEJ60731.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c18130 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.765
AEJ61545.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c12420 lipoprotein-releasing system ATP-binding protein LolD; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.736
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.