Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60481.1PFAM: Bacterial regulatory proteins, tetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: sta:STHERM_c02100 transcriptional activator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family. (239 aa)    
Predicted Functional Partners:
AEJ60479.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c02080 permease, involved in lipoprotein release; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
     0.802
AEJ60478.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c02070 permease involved in lipoprotein release; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
     0.800
AEJ60480.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c02090 ATP-binding/permease MacB; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
   
 
 0.786
AEJ60477.1
KEGG: sta:STHERM_c02060 outer membrane protein involved in lipoprotein sorting; SPTR: Putative uncharacterized protein.
     
 0.765
AEJ60476.1
KEGG: sta:STHERM_c02050 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.762
AEJ62282.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: cpo:COPRO5265_0205 transcriptional regulator, TetR family, putative; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
  
     0.692
AEJ61088.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c14190 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
  
     0.658
AEJ61847.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c15420 transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
  
     0.589
AEJ61971.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c16500 transcriptional regulatory protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
  
     0.551
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.506
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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