STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60489.1PFAM: Malate/L-lactate dehydrogenase; COGs: COG2055 Malate/L-lactate dehydrogenase; InterPro IPR003767; KEGG: sta:STHERM_c02180 ureidoglycolate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; SPTR: Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (338 aa)    
Predicted Functional Partners:
AEJ60486.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
    0.535
AEJ60490.1
KEGG: sta:STHERM_c02190 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.524
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
  
    0.516
AEJ60487.1
PFAM: Protein of unknown function DUF137; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; KEGG: sta:STHERM_c02160 hypothetical protein; PFAM: Protein of unknown function DUF137; SPTR: Pantothenate synthetase.
       0.515
AEJ60488.1
PFAM: GHMP kinases N terminal domain; COGs: COG1829 kinase (sugar kinase superfamily); InterPro IPR006204; KEGG: sta:STHERM_c02170 kinase; PFAM: GHMP kinase; SPTR: GHMP kinase.
       0.515
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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