STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60526.1Sugar isomerase (SIS); PFAM: SIS domain; COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: sta:STHERM_c02580 glucosamine--fructose-6-phosphate aminotransferase; PFAM: Sugar isomerase (SIS); SPTR: Sugar isomerase (SIS). (336 aa)    
Predicted Functional Partners:
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
0.939
AEJ60705.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: ace:Acel_2120 ribokinase-like domain-containing protein; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
  
 
 0.919
AEJ60527.1
LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: sta:STHERM_c02590 deacetylase; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: LmbE family protein.
 
   
 0.915
AEJ62078.1
PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: sta:STHERM_c17490 mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type I; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: Mannose-6-phosphate isomerase, type I.
    
  0.910
AEJ60553.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: sta:STHERM_c02830 glutamine synthetase, type 1; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
     
 0.903
AEJ60759.1
PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sta:STHERM_c18040 hypothetical protein; PFAM: ROK; SPTR: Fructokinase.
    
  0.903
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: sta:STHERM_c20070 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
  0.901
AEJ60450.1
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: sta:STHERM_c01790 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Mannose-1-phosphate guanylyltransferase.
     
  0.900
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
     
  0.900
AEJ61322.1
Glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006005; KEGG: sta:STHERM_c10250 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADH) small subunit; TIGRFAM: Glutamate synthase, NADH/NADPH, small subunit 1.
     
  0.900
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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