STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60527.1LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: sta:STHERM_c02590 deacetylase; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: LmbE family protein. (269 aa)    
Predicted Functional Partners:
AEJ60526.1
Sugar isomerase (SIS); PFAM: SIS domain; COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: sta:STHERM_c02580 glucosamine--fructose-6-phosphate aminotransferase; PFAM: Sugar isomerase (SIS); SPTR: Sugar isomerase (SIS).
 
   
 0.915
AEJ60528.1
PFAM: Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sta:STHERM_c02600 aldose-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase.
       0.800
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
    0.776
AEJ60529.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c02610 sugar ABC transporter sugar-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1.
 
     0.556
AEJ60532.1
PFAM: Glycosyl hydrolase family 20, catalytic domain; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883; KEGG: sta:STHERM_c02640 glycoside hydrolase, family 20; PFAM: Glycoside hydrolase, family 20, catalytic core; SPTR: Glycoside hydrolase, family 20, catalytic core.
 
   
 0.521
AEJ60524.1
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
       0.419
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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