STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60537.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (217 aa)    
Predicted Functional Partners:
AEJ61442.1
TIGRFAM: small redox-active disulfide protein 2; InterPro IPR005243; KEGG: sta:STHERM_c11400 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2.
  
 0.901
AEJ61670.1
Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: sta:STHERM_c07590 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase.
  
 
 0.844
AEJ62188.1
PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: fnu:FN2045 ferric uptake regulation protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; Belongs to the Fur family.
  
  
 0.718
AEJ62189.1
Ferritin Dps family protein; PFAM: Ferritin-like domain; COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331; KEGG: sta:STHERM_c18850 DNA protection during starvation protein; PFAM: Ferritin/Dps protein; SPTR: Ferritin Dps family protein; Belongs to the Dps family.
  
  
 0.702
AEJ62544.1
Regulatory protein ArsR; PFAM: Transcriptional regulator PadR-like family; InterPro IPR001845; KEGG: sta:STHERM_c22490 hypothetical protein; SMART: HTH transcriptional regulator, ArsR; SPTR: Regulatory protein ArsR.
  
    0.644
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.614
AEJ61075.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.595
AEJ60402.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: sta:STHERM_c01270 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.587
AEJ60457.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: sta:STHERM_c01860 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.587
AEJ60717.1
PFAM: Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: sta:STHERM_c04690 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin.
  
  
 0.536
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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