STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60555.1Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (425 aa)    
Predicted Functional Partners:
AEJ60556.1
KEGG: sta:STHERM_c02860 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.752
AEJ60554.1
PFAM: Uncharacterized conserved protein (DUF2156); COGs: COG4866 conserved hypothetical protein; InterPro IPR016732; KEGG: sta:STHERM_c02850 ABC transporter permease; PFAM: Uncharacterised conserved protein UCP018688; SPTR: Putative uncharacterized protein.
       0.615
AEJ60557.1
KEGG: sta:STHERM_c02870 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.597
AEJ61659.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
   
   0.574
AEJ60758.1
PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: sta:STHERM_c18050 hypothetical protein; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Peptidase M24.
 
 
 0.544
AEJ60558.1
KEGG: sta:STHERM_c02880 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.536
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.519
AEJ62442.1
PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: sta:STHERM_c21440 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: Putative uncharacterized protein; TIGRFAM: NGG1p interacting factor 3, NIF3.
  
    0.481
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
 0.440
AEJ60908.1
PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0006 Xaa-Pro aminopeptidase; KEGG: sta:STHERM_c06140 M24 family peptidase-like protein; SPTR: Putative uncharacterized protein.
  
 
 0.440
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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