Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rsmGRibosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (214 aa)    
Predicted Functional Partners:
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
  
 0.985
mnmE
tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
  
 0.981
AEJ62546.1
parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; COGs: COG1475 transcriptional regulator protein; InterPro IPR004437:IPR003115; KEGG: sta:STHERM_c22510 chromosome 1-partitioning protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein.
  
  
 0.707
AEJ61706.1
PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; InterPro IPR003115; KEGG: sta:STHERM_c07140 ParB-like nuclease domain-containing protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB domain protein nuclease.
  
  
 0.680
AEJ60296.1
Single-stranded nucleic acid binding R3H domain-containing protein; PFAM: R3H domain; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: sta:STHERM_c00090 hypothetical protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Single-stranded nucleic acid binding R3H domain-containing protein.
  
  
 0.656
AEJ60560.1
KEGG: sta:STHERM_c02900 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.593
AEJ62234.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.557
yidC
Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
  
 0.555
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
  
 
 
 0.483
AEJ62479.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c21780 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: ParaA family ATPase.
 
  
 0.468
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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