STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60566.1KEGG: sta:STHERM_c02960 hypothetical protein; SPTR: Putative uncharacterized protein. (151 aa)    
Predicted Functional Partners:
aroE
3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.671
AEJ60565.1
Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: sta:STHERM_c02950 sensory box/GGDEF family protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase.
       0.661
AEJ60564.1
PFAM: Restriction endonuclease; InterPro IPR001440:IPR013105:IPR007560:IPR019734; KEGG: sta:STHERM_c02940 TPR domain-containing protein; PFAM: Restriction endonuclease, type IV-like, Mrr; Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Restriction endonuclease.
       0.467
AEJ60568.1
PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: sta:STHERM_c02980 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Carboxynorspermidine dehydrogenase.
       0.429
AEJ60569.1
PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase; COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183:IPR005730; KEGG: sta:STHERM_c02990 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase.
       0.429
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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