STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60568.1PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: sta:STHERM_c02980 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Carboxynorspermidine dehydrogenase. (397 aa)    
Predicted Functional Partners:
AEJ60569.1
PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase; COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183:IPR005730; KEGG: sta:STHERM_c02990 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase.
 
  
 0.961
lysA
Orn/DAP/Arg decarboxylase 2; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 
 0.919
AEJ62383.1
PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein; COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: sta:STHERM_c20840 L-lysine 2,3-aminomutase; PFAM: Radical SAM; SPTR: Lysine 2,3-aminomutase YodO family protein; TIGRFAM: Protein of unknown function DUF160.
     
  0.900
AEJ60570.1
Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005925; KEGG: sta:STHERM_c03000 agmatinase; PFAM: Ureohydrolase; SPTR: Agmatinase; TIGRFAM: Putative agmatinase; Belongs to the arginase family.
   
 0.874
aroE
3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.541
AEJ60571.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: sta:STHERM_c03010 AMP-binding enzyme family protein; PFAM: AMP-dependent synthetase/ligase; SPTR: AMP-dependent synthetase and ligase.
  
  
 0.529
AEJ60566.1
KEGG: sta:STHERM_c02960 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.429
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.