STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
AEJ60570.1Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005925; KEGG: sta:STHERM_c03000 agmatinase; PFAM: Ureohydrolase; SPTR: Agmatinase; TIGRFAM: Putative agmatinase; Belongs to the arginase family. (291 aa)    
Predicted Functional Partners:
AEJ60569.1
PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase; COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183:IPR005730; KEGG: sta:STHERM_c02990 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase.
 
 
 0.979
AEJ60568.1
PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: sta:STHERM_c02980 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Carboxynorspermidine dehydrogenase.
   
 0.884
AEJ60865.1
Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
 
 
 0.758
leuS
PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015945:IPR013155; KEGG: sta:STHERM_c03870 leucyl-tRNA synthetase; PFAM: Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Arginyl-tRNA synthetase, class Ic, core; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.693
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
    
 0.571
AEJ60571.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: sta:STHERM_c03010 AMP-binding enzyme family protein; PFAM: AMP-dependent synthetase/ligase; SPTR: AMP-dependent synthetase and ligase.
  
    0.565
AEJ62312.1
PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR005814:IPR004636; KEGG: sta:STHERM_c20050 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase.
  
 
 0.554
aroE
3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
     
 0.493
AEJ61711.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014:IPR003661:IPR003594; KEGG: sta:STHERM_c07090 sensor protein ZraS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PA [...]
  
 0.449
AEJ61466.1
PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase.
  
 
 0.433
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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