STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60572.1KEGG: sta:STHERM_c03020 hypothetical protein; SPTR: Putative uncharacterized protein. (246 aa)    
Predicted Functional Partners:
AEJ60573.1
KEGG: sta:STHERM_c03030 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.636
AEJ60575.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003594; KEGG: sta:STHERM_c03060 nitrogen regulation protein; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; SMART: ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase.
       0.474
AEJ60576.1
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: sta:STHERM_c03070 two component, sigma-54 specific, transcriptional regulator, fis family nitrogen assimilation; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type [...]
       0.474
AEJ60571.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: sta:STHERM_c03010 AMP-binding enzyme family protein; PFAM: AMP-dependent synthetase/ligase; SPTR: AMP-dependent synthetase and ligase.
       0.444
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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