STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60585.1PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; COGs: COG2871 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrF; InterPro IPR001041:IPR008333:IPR001433; KEGG: sta:STHERM_c03160 Na(+)-translocating NADH-quinone reductase subunit F; PFAM: Oxidoreductase FAD-binding region; Ferredoxin; Oxidoreductase FAD/NAD(P)-binding; SPTR: Oxidoreductase FAD-binding domain protein. (368 aa)    
Predicted Functional Partners:
AEJ60583.1
PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit; COGs: COG1347 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrD; InterPro IPR003667:IPR011292; KEGG: sta:STHERM_c03140 Na(+)-translocating NADH-quinone reductase subunit D; PFAM: Electron transport complex, Rnf/Nqr; SPTR: NADH:ubiquinone oxidoreductase, subunit D; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit; Belongs to the NqrDE/RnfAE family.
 
 
 0.994
rnfA
RnfA-Nqr electron transport subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
 
 0.992
AEJ60581.1
PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR004338; KEGG: sta:STHERM_c03120 NADH:ubiquinone oxidoreductase, Na translocating, B subunit; PFAM: NADH-quinone reductase NQR2/RnfD; SPTR: NQR2 and RnfD family protein.
 
 
 0.980
rnfG
FMN-binding domain protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
 
   
 0.950
AEJ60586.1
KEGG: sta:STHERM_c03170 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.936
AEJ60587.1
PFAM: HEPN domain; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: sta:STHERM_c03180 HEPN domain-containing protein; PFAM: HEPN; SMART: HEPN; SPTR: HEPN domain protein.
       0.623
AEJ60588.1
DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; InterPro IPR002934; KEGG: sta:STHERM_c03190 nucleotidyltransferase domain-containing protein; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase beta domain protein region.
       0.623
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
       0.533
AEJ60486.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 
 0.482
AEJ60589.1
KEGG: sta:STHERM_c03200 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.472
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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