STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60593.1Transporter; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein; COGs: COG4213 ABC-type xylose transport system periplasmic component; KEGG: sta:STHERM_c03240 transporter; SPTR: D-xylose ABC transporter (Substrate-binding protein). (360 aa)    
Predicted Functional Partners:
AEJ60595.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG4214 ABC-type xylose transport system permease component; InterPro IPR001851; KEGG: sta:STHERM_c03260 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator.
 
 0.985
AEJ60594.1
PFAM: ABC transporter; COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c03250 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Xylose ABC transporter ATP-binding protein.
  
 0.853
AEJ61600.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08350 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
   
 0.723
AEJ62354.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c20550 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Transporter.
   
 0.689
AEJ61601.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08340 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator.
   
 0.682
AEJ60708.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ebd:ECBD_0922 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
   
 0.659
AEJ60591.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: ABC transporter; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; COGs: COG1129 ABC-type sugar transport system ATPase component; InterProIPR003593:IPR000014:IPR003661:IPR003594:IPR 003439:IPR013767; KEGG: sta:STHERM_c03220 sensory histidine kinase in two-component regulatory system with AtoC; PFAM: ATP-binding region, ATPase-like; ABC transporter-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding regi [...]
 
  
 0.613
AEJ61603.1
PFAM: family; TIGRFAM: rhamnose ABC transporter, rhamnose-binding protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR013459; KEGG: sta:STHERM_c08320 transporter; SPTR: Rhamnose-binding protein; TIGRFAM: Rhamnose ABC transporter, rhamnose-binding.
 
  
 0.527
AEJ62060.1
Regulatory protein MarR; PFAM: ROK family; MarR family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000835:IPR000600; KEGG: sta:STHERM_c17300 transcriptional repressor; PFAM: HTH transcriptional regulator, MarR; ROK; SPTR: Regulatory protein MarR.
 
     0.517
xylA
PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; COGs: COG2115 Xylose isomerase; HAMAP: Xylose isomerase; InterPro IPR013452:IPR012307:IPR001998; KEGG: sta:STHERM_c16290 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase; TIGRFAM: Xylose isomerase, bacterial type; Belongs to the xylose isomerase family.
 
  
 0.509
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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