STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60612.1PFAM: Protein of unknown function DUF124; TIGRFAM: TIGR00266 family protein; COGs: COG2013 conserved hypothetical protein; InterPro IPR002838; KEGG: sta:STHERM_c03580 HTH DNA-binding protein; PFAM: Protein of unknown function DUF124; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF124. (246 aa)    
Predicted Functional Partners:
AEJ60613.1
PFAM: Predicted ATPase of the ABC class; COGs: COG3044 ATPase of the ABC class; InterPro IPR019195; KEGG: sta:STHERM_c03590 isopentenyl-diphosphate delta-isomerase; PFAM: ABC transporter, ATPase, predicted; SPTR: ABC transporter, ATPase, predicted.
       0.610
AEJ60610.1
FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221:IPR004101; KEGG: sta:STHERM_c03390 folylpolyglutamate synthase; PFAM: Mur ligase, C-terminal; Mur ligase, central; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase.
       0.537
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.537
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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