STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEJ60614.1Multi-sensor signal transduction histidine kinase; PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; TIGRFAM: ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR003594:IPR013767:IPR008207; KEGG: sta:STHERM_c03600 ammonia permease with sensory box/GGDEF domains; PFAM: Ammonium transporter; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: Ammoni [...] (924 aa)    
Predicted Functional Partners:
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
 
 
 0.996
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
 
 0.991
AEJ62052.1
MCP methyltransferase, CheR-type; PFAM: CheW-like domain; CheR methyltransferase, SAM binding domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545:IPR000780; KEGG: sta:STHERM_c17220 chemotaxis protein CheW; PFAM: MCP methyltransferase, CheR-type; CheW-like protein; SMART: CheW-like protein; MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type.
  
 
 0.981
AEJ61109.1
PFAM: Nitrogen regulatory protein P-II; COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: sta:STHERM_c13230 transcriptional regulatory protein; PFAM: Nitrogen regulatory protein PII; SPTR: Nitrogen regulatory protein P-II.
 
 
 0.979
AEJ61090.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR003661:IPR003594:IPR 001789:IPR008207; KEGG: sta:STHERM_c14170 two-component system, sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; Signal transduction response regulator, receiver region; Signal transducti [...]
 
 0.963
AEJ60416.1
Integral membrane sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR001789; KEGG: sta:STHERM_c01410 transcriptional regulatory protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine [...]
 
 0.960
AEJ61668.1
Flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: sta:STHERM_c07620 flagellar hook-associated protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK.
  
  
 0.957
AEJ60864.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013767; KEGG: sta:STHERM_c05640 hypothetical protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; PAS fold-4; Signal transduction response regulator, receiver region; SMAR [...]
 
 0.955
AEJ61972.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 008207:IPR013767:IPR013656; KEGG: sta:STHERM_c16510 autoinducer 2 sensor kinase/phosphatase LuxQ; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; PAS fold; Signal transduction response regulator, receiver region [...]
 
 0.955
AEJ61206.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
  
 0.953
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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