Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEJ60618.1KEGG: sta:STHERM_c03640 hypothetical protein; SPTR: Putative uncharacterized protein. (448 aa)    
Predicted Functional Partners:
AEJ60619.1
KEGG: sta:STHERM_c03650 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ60620.1
Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: sta:STHERM_c03660 HIT-like protein tag-202; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein.
       0.563
AEJ60617.1
Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: sta:STHERM_c03630 automatic annotation; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047.
       0.542
AEJ62333.1
Protein of unknown function UPF0005; PFAM: Uncharacterised protein family UPF0005; COGs: COG0670 Integral membrane protein interacts with FtsH; InterPro IPR006214; KEGG: sta:STHERM_c20350 hypothetical protein; PFAM: Uncharacterised protein family UPF0005; SPTR: Putative uncharacterized protein; Belongs to the BI1 family.
  
  
 0.405
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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