Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEJ60620.1Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: sta:STHERM_c03660 HIT-like protein tag-202; PFAM: Histidine triad (HIT) protein; SPTR: Histidine triad (HIT) protein. (114 aa)    
Predicted Functional Partners:
AEJ60553.1
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: sta:STHERM_c02830 glutamine synthetase, type 1; PFAM: Glutamine synthetase, catalytic region; Glutamine synthetase, beta-Grasp; SPTR: Glutamine synthetase; TIGRFAM: Glutamine synthetase type I.
   
   0.657
AEJ60618.1
KEGG: sta:STHERM_c03640 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.563
AEJ60619.1
KEGG: sta:STHERM_c03650 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.554
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
   
   0.463
AEJ61504.1
TGS domain-containing protein; PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR003593:IPR004095; KEGG: sta:STHERM_c11970 hypothetical protein; PFAM: TGS; SMART: ATPase, AAA+ type, core; SPTR: TGS domain-containing protein.
   
 0.458
AEJ60617.1
Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: sta:STHERM_c03630 automatic annotation; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047.
       0.402
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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