STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
AEJ60627.1Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c03740 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN. (151 aa)    
Predicted Functional Partners:
AEJ60626.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: DNA binding domain, excisionase family; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR010093:IPR002178; KEGG: sta:STHERM_c03730 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: Excisionase/Xis, DNA-binding.
 
  
 
0.982
AEJ62536.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c22360 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
 
0.966
AEJ62080.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: sta:STHERM_c17500 sugar kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
 
  
 0.800
AEJ60628.1
PFAM: CBS domain; Sodium/hydrogen exchanger family; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR000644:IPR006153; KEGG: sta:STHERM_c03750 sodium/hydrogen exchanger family protein; PFAM: Cation/H+ exchanger; Cystathionine beta-synthase, core; SPTR: Sodium/hydrogen exchanger.
       0.786
AEJ61132.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
   
 0.746
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
 
  
 0.587
AEJ60630.1
Transposase IS3/IS911 family protein; PFAM: Integrase core domain; Transposase; InterPro IPR002514; KEGG: tye:THEYE_A0843 ISCc3, transposase OrfA; PFAM: Transposase IS3/IS911; SPTR: Transposase IS3/IS911 family protein; manually curated.
  
    0.518
AEJ61612.1
PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: sta:STHERM_c08230 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family.
 
  
 0.517
AEJ60629.1
KEGG: rmr:Rmar_2140 transposase-like protein; SPTR: Transposase-like protein.
       0.515
AEJ60753.1
PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: ssm:Spirs_1025 transcriptional regulator, DeoR family; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family.
 
  
 0.496
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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