Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60642.1Glycoside hydrolase family 42 domain protein; PFAM: Beta-galactosidase trimerisation domain; Beta-galactosidase C-terminal domain; Beta-galactosidase; COGs: COG1874 Beta-galactosidase; InterPro IPR013529:IPR013738:IPR013739; KEGG: sta:STHERM_c03920 beta-galactosidase; PFAM: Glycoside hydrolase, family 42, N-terminal; Beta-galactosidase trimerisation; Beta-galactosidase C-terminal; SPTR: Beta-galactosidase. (691 aa)    
Predicted Functional Partners:
AEJ60646.1
Glycoside hydrolase clan GH-D; PFAM: Melibiase; COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: sta:STHERM_c03960 alpha-galactosidase; PFAM: Glycoside hydrolase, clan GH-D; SPTR: Glycoside hydrolase clan GH-D.
 
  
 0.938
AEJ62193.1
PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103; KEGG: sta:STHERM_c18890 carbohydrate binding family 6; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase family 2, TIM barrel; SPTR: Glycoside hydrolase family 2 sugar binding.
 
 
 0.931
AEJ60524.1
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
 0.911
AEJ60528.1
PFAM: Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sta:STHERM_c02600 aldose-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase.
  
 
 0.911
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
     
  0.900
AEJ60650.1
PFAM: Glycosyl hydrolases family 31; COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: sta:STHERM_c03990 glycoside hydrolase, family 31; PFAM: Glycoside hydrolase, family 31; SPTR: Glycoside hydrolase family 31.
 
  
 0.638
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
   0.633
AEJ60641.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018060:IPR000005; KEGG: sta:STHERM_c03910 transcriptional regulator, AraC family; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
    0.606
AEJ60655.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c04040 polysaccharide ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
 
   
 0.554
AEJ60640.1
PFAM: Domain of unknown function (DUF3502); Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c03900 ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1.
 
   
 0.551
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.