Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60648.1PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; COGs: COG0153 Galactokinase; InterPro IPR000705:IPR019539:IPR006204:IPR013750; KEGG: sta:STHERM_c03980 galactokinase; PFAM: GHMP kinase; Galactokinase galactose-binding domain; GHMP kinase, C-terminal; SPTR: Galactokinase; TIGRFAM: Galactokinase. (350 aa)    
Predicted Functional Partners:
AEJ60647.1
PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1; COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR001937:IPR005849:IPR005850; KEGG: sta:STHERM_c03970 galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, N-terminal; Galactose-1-phosphate uridyl transferase, C-terminal; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: Galactose-1-phosphate uridyl transferase, class I.
 0.999
AEJ60524.1
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 0.984
AEJ60528.1
PFAM: Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sta:STHERM_c02600 aldose-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase.
 
 0.968
AEJ60646.1
Glycoside hydrolase clan GH-D; PFAM: Melibiase; COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: sta:STHERM_c03960 alpha-galactosidase; PFAM: Glycoside hydrolase, clan GH-D; SPTR: Glycoside hydrolase clan GH-D.
 
  
 0.923
AEJ61164.1
PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; COGs: COG0153 Galactokinase; InterPro IPR019539:IPR006204:IPR013750; KEGG: sta:STHERM_c12660 hypothetical protein; PFAM: GHMP kinase; Galactokinase galactose-binding domain; GHMP kinase, C-terminal; SPTR: Galactokinase.
  
  
 
0.920
AEJ60643.1
UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR005886:IPR001509; KEGG: sta:STHERM_c03930 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-galactose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase.
 
 
 0.910
AEJ60645.1
PFAM: Glycosyl hydrolase family 53; COGs: COG3867 Arabinogalactan endo-1 4-beta-galactosidase; InterPro IPR011683; KEGG: sta:STHERM_c03950 arabinogalactan endo-1,4-beta-galactosidase; PFAM: Glycosyl hydrolase 53; SPTR: Arabinogalactan endo-1,4-beta-galactosidase.
     
 0.519
AEJ60649.1
Hypothetical protein.
       0.470
AEJ60726.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sta:STHERM_c18190 hypothetical protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
  
 
 0.400
AEJ60912.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sta:STHERM_c06180 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
  
 
 0.400
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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