Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60650.1PFAM: Glycosyl hydrolases family 31; COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: sta:STHERM_c03990 glycoside hydrolase, family 31; PFAM: Glycoside hydrolase, family 31; SPTR: Glycoside hydrolase family 31. (761 aa)    
Predicted Functional Partners:
AEJ61442.1
TIGRFAM: small redox-active disulfide protein 2; InterPro IPR005243; KEGG: sta:STHERM_c11400 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2.
    
 0.658
AEJ60642.1
Glycoside hydrolase family 42 domain protein; PFAM: Beta-galactosidase trimerisation domain; Beta-galactosidase C-terminal domain; Beta-galactosidase; COGs: COG1874 Beta-galactosidase; InterPro IPR013529:IPR013738:IPR013739; KEGG: sta:STHERM_c03920 beta-galactosidase; PFAM: Glycoside hydrolase, family 42, N-terminal; Beta-galactosidase trimerisation; Beta-galactosidase C-terminal; SPTR: Beta-galactosidase.
 
  
 0.638
AEJ60651.1
PFAM: Glycosyl hydrolase family 3 C terminal domain; Fascin domain; Glycosyl hydrolase family 3 N terminal domain; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR002772; KEGG: sta:STHERM_c04000 glucan 1,4-beta-glucosidase; PFAM: Glycoside hydrolase, family 3, C-terminal; Glycoside hydrolase, family 3, N-terminal; SPTR: Beta-glucosidase; manually curated.
 
   
 0.593
AEJ60645.1
PFAM: Glycosyl hydrolase family 53; COGs: COG3867 Arabinogalactan endo-1 4-beta-galactosidase; InterPro IPR011683; KEGG: sta:STHERM_c03950 arabinogalactan endo-1,4-beta-galactosidase; PFAM: Glycosyl hydrolase 53; SPTR: Arabinogalactan endo-1,4-beta-galactosidase.
 
   
 0.579
AEJ60652.1
Transcriptional regulator with cupin sensor, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: sta:STHERM_c04010 transcriptional regulator, AraC/XylS family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
     
 0.510
AEJ60655.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c04040 polysaccharide ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
 
    0.488
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.472
AEJ60657.1
Glycosyl hydrolase BNR repeat-containing protein; PFAM: BNR/Asp-box repeat; InterPro IPR002860; KEGG: cth:Cthe_1398 cellulosome enzyme, dockerin type I; PFAM: BNR repeat; SPTR: Cellulosome enzyme, dockerin type I; manually curated.
 
     0.470
AEJ62193.1
PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103; KEGG: sta:STHERM_c18890 carbohydrate binding family 6; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase family 2, TIM barrel; SPTR: Glycoside hydrolase family 2 sugar binding.
 
  
 0.466
AEJ60649.1
Hypothetical protein.
       0.458
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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