STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60652.1Transcriptional regulator with cupin sensor, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: sta:STHERM_c04010 transcriptional regulator, AraC/XylS family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family. (305 aa)    
Predicted Functional Partners:
AEJ62404.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR003313:IPR000005:IPR018060; KEGG: sta:STHERM_c21040 transcriptional regulatory protein; PFAM: AraC protein, arabinose-binding/dimerisation; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
0.826
AEJ60651.1
PFAM: Glycosyl hydrolase family 3 C terminal domain; Fascin domain; Glycosyl hydrolase family 3 N terminal domain; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR002772; KEGG: sta:STHERM_c04000 glucan 1,4-beta-glucosidase; PFAM: Glycoside hydrolase, family 3, C-terminal; Glycoside hydrolase, family 3, N-terminal; SPTR: Beta-glucosidase; manually curated.
       0.714
AEJ60654.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c04030 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family.
 
   
 0.707
AEJ60653.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c04020 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
       0.648
AEJ61692.1
Flagellar basal-body rod protein FlgG; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria; COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444:IPR010930:IPR020013:IPR012834; KEGG: sta:STHERM_c07300 flagellar basal-body rod protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: Flagellar basal-bod [...]
    
   0.648
AEJ61693.1
Flagellar basal-body rod protein FlgF; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444:IPR010930:IPR020013:IPR012836; KEGG: sta:STHERM_c07290 flagellar hook-basal body complex protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar hook-basal body complex protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE [...]
    
   0.648
AEJ60655.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c04040 polysaccharide ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
 
   
 0.641
AEJ60697.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.614
AEJ61309.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.614
rpoD
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.614
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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