STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEJ60672.1Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c04220 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR. (246 aa)    
Predicted Functional Partners:
AEJ62451.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.953
AEJ61582.1
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; PFAM: FabA-like domain; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: sta:STHERM_c08550 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA/FabZ.
 
 0.939
fabH
3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.912
AEJ60671.1
PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit; COGs: COG1593 TRAP-type C4-dicarboxylate transport system large permease component; InterPro IPR004681:IPR010656; KEGG: sta:STHERM_c04210 transporter; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP dicarboxylate transporter, DctM subunit; TIGRFAM: TRAP dicarboxylate transporter, DctM subunit.
       0.633
AEJ61591.1
PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain; InterPro IPR013737:IPR008902; KEGG: sta:STHERM_c08460 alfa-L-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase; Bacterial alpha-L-rhamnosidase N-terminal; SPTR: Alpha-L-rhamnosidase.
   
 
 0.601
AEJ62453.1
PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043; KEGG: sta:STHERM_c21550 hypothetical protein; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase.
 
 0.594
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
 
 
 0.581
AEJ62080.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: sta:STHERM_c17500 sugar kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
  
  
 0.569
AEJ60669.1
TRAP dicarboxylate transporter, DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR004682:IPR018389; KEGG: sta:STHERM_c04190 transporter; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: TRAP dicarboxylate transporter, DctP subunit; TIGRFAM: TRAP dicarboxylate transporter, DctP subunit.
       0.543
AEJ60670.1
PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component; COGs: COG3090 TRAP-type C4-dicarboxylate transport system small permease component; InterPro IPR007387; KEGG: sta:STHERM_c04200 transporter; PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; SPTR: Tripartite ATP-independent periplasmic transporter DctQ component.
       0.542
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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