STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60681.1PFAM: Glycosyl hydrolases family 28; COGs: COG5434 Endopygalactorunase; InterPro IPR006626:IPR000743; KEGG: sta:STHERM_c04310 hypothetical protein; PFAM: Glycoside hydrolase, family 28; SPTR: Glycoside hydrolase family 28. (462 aa)    
Predicted Functional Partners:
AEJ60661.1
PFAM: Glycosyl Hydrolase Family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sta:STHERM_c04120 unsaturated glucuronyl hydrolase; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
   
 0.945
AEJ61616.1
PFAM: Glycosyl Hydrolase Family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sta:STHERM_c08190 glycosyl hydrolase, family 88; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
 
   
 0.746
kduI
4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.706
AEJ61963.1
PFAM: Domain of unknown function (DUF303); Glycosyl hydrolases family 2, sugar binding domain; InterPro IPR005181:IPR006104; KEGG: sta:STHERM_c16420 sialic acid-specific 9-O-acetylesterase; PFAM: Protein of unknown function DUF303, acetylesterase putative; Glycoside hydrolase family 2, carbohydrate-binding; SPTR: Putative uncharacterized protein.
 
 
 0.698
AEJ61585.1
KEGG: sta:STHERM_c08520 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.693
AEJ60684.1
PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c04340 xylose isomerase domain-containing protein TIM barrel; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel.
 
     0.667
AEJ60680.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c04300 extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1.
 
   
 0.615
AEJ61054.1
PFAM: Domain of unknown function (DUF303); InterPro IPR005181; KEGG: sta:STHERM_c14530 sialate O-acetylesterase precursor; PFAM: Protein of unknown function DUF303, acetylesterase putative; SPTR: Sialate O-acetylesterase.
 
 
 0.607
AEJ62403.1
Beta-galactosidase; PFAM: Glycosyl hydrolase family 1; TIGRFAM: beta-galactosidase; COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR017736:IPR001360; KEGG: sta:STHERM_c21030 beta-glucosidase A; PFAM: Glycoside hydrolase, family 1; SPTR: Broad-specificity cellobiase; TIGRFAM: Glycoside hydrolase, family 1, beta-glucosidase.
   
   0.603
AEJ61619.1
Sporulation domain-containing protein; PFAM: Sporulation related domain; InterPro IPR005132:IPR007730; KEGG: sta:STHERM_c08160 hypothetical protein; PFAM: Sporulation/cell division region, bacteria; Rare lipoprotein A; SPTR: Sporulation domain-containing protein.
   
 
 0.546
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.