STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60682.1PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sta:STHERM_c04320 carbohydrate kinase, PfkB family; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein. (366 aa)    
Predicted Functional Partners:
AEJ60683.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sta:STHERM_c04330 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; SPTR: 2-keto-3-deoxy-phosphogluconate aldolase.
 
 
 0.995
AEJ60700.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c04590 D-mannonate oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
 
 0.880
AEJ60684.1
PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c04340 xylose isomerase domain-containing protein TIM barrel; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel.
  
  
 0.872
AEJ61985.1
PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: sta:STHERM_c16660 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase.
  
 0.871
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.867
AEJ60685.1
KEGG: sta:STHERM_c04350 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.866
AEJ60663.1
PFAM: short chain dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR011286:IPR002198; KEGG: sta:STHERM_c04140 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 2-deoxy-D-gluconate 3-dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase.
 
 0.851
araB
Ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase; COGs: COG1069 Ribulose kinase; HAMAP: L-ribulokinase; InterPro IPR018484:IPR018485:IPR005929; KEGG: sta:STHERM_c20530 ribulokinase; PFAM: Carbohydrate kinase, FGGY, C-terminal; Carbohydrate kinase, FGGY, N-terminal; SPTR: Ribulokinase.
    
 0.810
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
  
  
 0.770
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; InterPro IPR006062; KEGG: sta:STHERM_c01300 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; PFAM: Histidine b [...]
  
  
 0.614
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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