STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60684.1PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c04340 xylose isomerase domain-containing protein TIM barrel; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel. (291 aa)    
Predicted Functional Partners:
AEJ62350.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: sta:STHERM_c20510 L-ribulose-5-phosphate 4-epimerase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: L-ribulose 5-phosphate 4-epimerase.
  
 
 0.912
araB
Ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase; COGs: COG1069 Ribulose kinase; HAMAP: L-ribulokinase; InterPro IPR018484:IPR018485:IPR005929; KEGG: sta:STHERM_c20530 ribulokinase; PFAM: Carbohydrate kinase, FGGY, C-terminal; Carbohydrate kinase, FGGY, N-terminal; SPTR: Ribulokinase.
     
 0.902
AEJ60682.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sta:STHERM_c04320 carbohydrate kinase, PfkB family; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
  
  
 0.872
AEJ60683.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sta:STHERM_c04330 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; SPTR: 2-keto-3-deoxy-phosphogluconate aldolase.
  
    0.787
AEJ60685.1
KEGG: sta:STHERM_c04350 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ61616.1
PFAM: Glycosyl Hydrolase Family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sta:STHERM_c08190 glycosyl hydrolase, family 88; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
 
    0.725
AEJ60661.1
PFAM: Glycosyl Hydrolase Family 88; COGs: COG4225 unsaturated glucuronyl hydrolase involved in regulation of surface properties and related protein; InterPro IPR010905; KEGG: sta:STHERM_c04120 unsaturated glucuronyl hydrolase; PFAM: Glycosyl hydrolase, family 88; SPTR: Glycosyl hydrolase family 88.
 
    0.699
AEJ60681.1
PFAM: Glycosyl hydrolases family 28; COGs: COG5434 Endopygalactorunase; InterPro IPR006626:IPR000743; KEGG: sta:STHERM_c04310 hypothetical protein; PFAM: Glycoside hydrolase, family 28; SPTR: Glycoside hydrolase family 28.
 
     0.667
kduI
4-deoxy-L-threo-5-hexosulose-uronateketol- isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
     0.630
AEJ60726.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sta:STHERM_c18190 hypothetical protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
  
  
 0.622
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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