Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbsDD-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (133 aa)    
Predicted Functional Partners:
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 
 0.882
AEJ62355.1
Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: sta:STHERM_c20560 ribose ABC transporter; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.821
AEJ62354.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c20550 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Transporter.
 
  
 0.810
AEJ60708.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ebd:ECBD_0922 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
 
  
 0.808
AEJ60709.1
Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: pjd:Pjdr2_5327 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.777
AEJ60690.1
L-fucose isomerase-like protein; PFAM: L-fucose isomerase, C-terminal domain; COGs: COG2407 L-fucose isomerase and related protein; InterPro IPR012889:IPR015888; KEGG: ssm:Spirs_1033 L-fucose isomerase; PFAM: L-fucose isomerase-like, C-terminal; L-fucose isomerase, N-terminal-2; SPTR: L-fucose isomerase.
       0.759
AEJ60380.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: sta:STHERM_c01060 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer.
  
  
 0.751
AEJ61600.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08350 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
  
  
 0.745
AEJ61601.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08340 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Inner-membrane translocator.
  
  
 0.745
AEJ61603.1
PFAM: family; TIGRFAM: rhamnose ABC transporter, rhamnose-binding protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR013459; KEGG: sta:STHERM_c08320 transporter; SPTR: Rhamnose-binding protein; TIGRFAM: Rhamnose ABC transporter, rhamnose-binding.
  
  
 0.741
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.