Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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AEJ60694.1PFAM: Glycosyltransferase family 28 C-terminal domain; Monogalactosyldiacylglycerol (MGDG) synthase; COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR007235; KEGG: sta:STHERM_c04530 monogalactosyldiacylglycerol synthase; PFAM: Glycosyl transferase, family 28, C-terminal; SPTR: Glycosyltransferase 28 domain. (378 aa)    
Predicted Functional Partners:
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.885
AEJ61196.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
  
 0.867
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.785
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
  
 0.774
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
 
 0.731
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
 
 
 0.655
AEJ60693.1
KEGG: sta:STHERM_c04520 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.634
AEJ61195.1
PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437; KEGG: sta:STHERM_c08960 hypothetical protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: Cell division protein FtsW; Belongs to the SEDS family.
  
  
 0.592
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 0.592
AEJ60893.1
D-alanine--D-alanine ligase domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
  
 0.572
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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