STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxaCPFAM: Glucuronate isomerase; COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: sta:STHERM_c04600 uronate isomerase; PFAM: Uronate isomerase; SPTR: Uronate isomerase. (469 aa)    
Predicted Functional Partners:
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.970
AEJ60685.1
KEGG: sta:STHERM_c04350 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.926
AEJ61617.1
PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: sta:STHERM_c08180 hydrolytic enzyme; PFAM: Glycoside hydrolase, family 4; SPTR: Glycoside hydrolase family 4.
 
  
  0.915
AEJ60896.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: sta:STHERM_c06020 hypothetical protein; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; SPTR: Alcohol dehydrogenase GroES domain protein.
     
 0.905
AEJ62350.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: sta:STHERM_c20510 L-ribulose-5-phosphate 4-epimerase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: L-ribulose 5-phosphate 4-epimerase.
    
 0.834
AEJ61025.1
alpha-L-arabinofuranosidase domain protein; PFAM: Alpha-L-arabinofuranosidase C-terminus; COGs: COG3534 Alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: sta:STHERM_c14770 alpha-N-arabinofuranosidase; PFAM: Alpha-L-arabinofuranosidase, C-terminal; SMART: Alpha-L-arabinofuranosidase, C-terminal; SPTR: Alpha-N-arabinofuranosidase.
     
 0.821
AEJ61026.1
alpha-L-arabinofuranosidase domain protein; PFAM: Alpha-L-arabinofuranosidase C-terminus; COGs: COG3534 Alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: sta:STHERM_c14760 alpha-N-arabinofuranosidase 2; PFAM: Alpha-L-arabinofuranosidase, C-terminal; SMART: Alpha-L-arabinofuranosidase, C-terminal; SPTR: Alpha-L-arabinofuranosidase domain protein.
     
 0.821
AEJ62151.1
PFAM: Glycosyl hydrolases family 43; COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: sta:STHERM_c18500 beta-xylosidase; PFAM: Glycoside hydrolase, family 43; SPTR: Xylan 1,4-beta-xylosidase.
    
 0.810
AEJ60700.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c04590 D-mannonate oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
 
  
 0.799
AEJ60683.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sta:STHERM_c04330 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; SPTR: 2-keto-3-deoxy-phosphogluconate aldolase.
 
   
 0.575
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (24%) [HD]