STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysSPFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; COGs: COG1384 Lysyl-tRNA synthetase (class I); HAMAP: Lysyl-tRNA synthetase, class I, archaeal-type; InterPro IPR002904:IPR020756:IPR020754; KEGG: sta:STHERM_c04620 hypothetical protein; PFAM: Lysyl-tRNA synthetase, class Ic; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class I; Belongs to the class-I aminoacyl-tRNA synthetase family. (530 aa)    
Predicted Functional Partners:
cmk-2
PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase, putative; COGs: COG1102 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR000623:IPR011892; KEGG: sta:STHERM_c12230 cytidylate kinase; PFAM: Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase, putative.
  
     0.676
AEJ62522.1
Glycoside hydrolase family 37; PFAM: Trehalase; COGs: COG1626 Neutral trehalase; InterPro IPR001661; KEGG: sta:STHERM_c22220 hypothetical protein; PFAM: Glycoside hydrolase, family 37; SPTR: Glycoside hydrolase family 37.
  
     0.670
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
       0.564
pheS
PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain; InterPro IPR004529:IPR002319; KEGG: sta:STHERM_c21750 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase alpha chain; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
  
    0.564
AEJ61626.1
Protein of unknown function YGGT; PFAM: YGGT family; InterPro IPR003425; KEGG: sta:STHERM_c08080 hypothetical protein; PFAM: Protein of unknown function YGGT; SPTR: Putative uncharacterized protein.
  
     0.536
AEJ62428.1
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
     0.536
AEJ61084.1
PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844; KEGG: sta:STHERM_c14230 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.
  
    0.532
AEJ60544.1
PFAM: Uncharacterised protein family (UPF0158); KEGG: sta:STHERM_c02740 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.525
pheT
Phenylalanyl-tRNA synthetase beta chain; PFAM: tRNA synthetases class II core domain (F); tRNA synthetase B5 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase beta chain; InterPro IPR004531:IPR005147; KEGG: sta:STHERM_c21760 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase, B5; SPTR: Phenylalanyl-tRNA synthetase beta chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic.
 
     0.525
AEJ61456.1
PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PPIC-type PPIASE domain; InterPro IPR000297; KEGG: sta:STHERM_c11500 hypothetical protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase.
  
     0.510
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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