STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60710.1PFAM: Bacterial regulatory proteins, lacI family; family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: transcriptional regulator, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Transcriptional regulator, LacI family. (332 aa)    
Predicted Functional Partners:
AEJ60542.1
PFAM: Bacterial regulatory proteins, luxR family; family; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR013767:IPR000792:IPR000014; KEGG: sta:STHERM_c02720 transcriptional regulator protein; PFAM: Transcription regulator LuxR, C-terminal; Periplasmic binding protein/LacI transcriptional regulator; PAS fold; SMART: Transcription regulator LuxR, C-terminal; SPTR: Transcriptional regulator, LuxR family; TIGRFAM: PAS.
  
     0.772
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
     
 0.707
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
    
 
 0.680
AEJ60709.1
Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: pjd:Pjdr2_5327 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator.
 
  
 0.619
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
   
 
 0.545
AEJ60705.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: ace:Acel_2120 ribokinase-like domain-containing protein; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
 
  
 0.486
AEJ60708.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ebd:ECBD_0922 inner-membrane translocator; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
  
  
 0.441
rbsA
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
  
  
 0.430
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.429
AEJ60712.1
KEGG: sta:STHERM_c04640 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.427
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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