STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60716.1Conserved hypothetical protein CHP02757; PFAM: Protein of unknown function (DUF2400); TIGRFAM: TIGR02757 family protein; InterPro IPR014127; KEGG: sta:STHERM_c04680 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: Putative uncharacterized protein. (276 aa)    
Predicted Functional Partners:
AEJ60717.1
PFAM: Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: sta:STHERM_c04690 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin.
       0.627
AEJ62230.1
Exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR004808:IPR000097; KEGG: sta:STHERM_c19260 hypothetical protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III Xth; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1.
  
 0.625
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
       0.590
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.576
AEJ60745.1
PFAM: Rnf-Nqr subunit, membrane protein; COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; KEGG: sta:STHERM_c04440 hypothetical protein; SPTR: Electron transport complex RsxE subunit; Belongs to the NqrDE/RnfAE family.
  
  
 0.503
rnfE
Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
  
  
 0.503
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
  
 0.483
AEJ61220.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG1360 Flagellar motor protein; InterPro IPR006665; KEGG: sta:STHERM_c09210 hypothetical protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: Putative uncharacterized protein.
  
 
   0.465
AEJ60718.1
Rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin; COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: sta:STHERM_c04700 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin.
       0.458
rnfG
FMN-binding domain protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
  
 0.432
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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