Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60717.1PFAM: Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: sta:STHERM_c04690 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin. (191 aa)    
Predicted Functional Partners:
AEJ60718.1
Rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin; COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: sta:STHERM_c04700 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin.
  
  
 0.745
AEJ60716.1
Conserved hypothetical protein CHP02757; PFAM: Protein of unknown function (DUF2400); TIGRFAM: TIGR02757 family protein; InterPro IPR014127; KEGG: sta:STHERM_c04680 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: Putative uncharacterized protein.
       0.627
AEJ61770.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: sta:STHERM_c13740 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
    
 0.585
AEJ60777.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG0426 flavoprotein; KEGG: sta:STHERM_c04740 hypothetical protein; SPTR: Uncharacterized flavoprotein.
 
  
 0.577
AEJ60537.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.561
AEJ62188.1
PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: fnu:FN2045 ferric uptake regulation protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; Belongs to the Fur family.
 
  
 0.548
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
     
 0.472
AEJ60506.1
PFAM: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin ferrous iron-binding domain; COGs: COG2033 Desulfoferrodoxin; InterPro IPR002742; KEGG: sta:STHERM_c02360 neelaredoxin; PFAM: Desulfoferrodoxin, ferrous iron-binding region; SPTR: Superoxide reductase; TIGRFAM: Desulfoferrodoxin, ferrous iron-binding region.
  
  
 0.438
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
     
 0.425
AEJ60920.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR001041:IPR019574:IPR001450:IPR 004108:IPR003149; KEGG: sta:STHERM_c06260 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
 
    
 0.420
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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