STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60730.1Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c18140 integral membrane protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein. (355 aa)    
Predicted Functional Partners:
AEJ60731.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c18130 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.966
AEJ60728.1
Protein of unknown function DUF2318, membrane; PFAM: Predicted membrane protein (DUF2318); COGs: COG4393 membrane protein; InterPro IPR018758; KEGG: sta:STHERM_c18160 hypothetical protein; PFAM: Protein of unknown function DUF2318, membrane; SPTR: Putative uncharacterized protein.
  
 0.954
AEJ60727.1
PFAM: Fe2+ transport protein; COGs: COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport; InterPro IPR018470; KEGG: sta:STHERM_c18170 hypothetical protein; PFAM: Ferrous iron transport protein, bacterial; SPTR: Ferrous iron transport protein.
 
    0.871
AEJ60729.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c18150 permease domain-containing protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
    
0.837
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.825
AEJ61306.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c10090 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Transporter; manually curated.
 
 
 0.790
AEJ60732.1
PFAM: FMN-binding domain; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: sta:STHERM_c18120 hypothetical protein; PFAM: FMN-binding; SPTR: FMN-binding domain protein.
       0.728
AEJ62237.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c19330 ABC-type transport system, permease; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
  
 0.713
AEJ62541.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c22460 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.708
AEJ61307.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c10100 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
  
 0.703
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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