Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60736.1PFAM: Peptidase family M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: sta:STHERM_c18080 aminopeptidase; PFAM: Peptidase M28; SPTR: Peptidase M28. (427 aa)    
Predicted Functional Partners:
AEJ60737.1
PFAM: Domain of unknown function (DUF369); COGs: COG2164 conserved hypothetical protein; InterPro IPR007256; KEGG: sta:STHERM_c18070 hypothetical protein; PFAM: Protein of unknown function DUF369; SPTR: Putative uncharacterized protein.
       0.773
AEJ60735.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c18090 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
       0.552
AEJ60738.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: bur:Bcep18194_A4897 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
       0.506
AEJ60570.1
Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005925; KEGG: sta:STHERM_c03000 agmatinase; PFAM: Ureohydrolase; SPTR: Agmatinase; TIGRFAM: Putative agmatinase; Belongs to the arginase family.
   
 
 0.429
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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