STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60737.1PFAM: Domain of unknown function (DUF369); COGs: COG2164 conserved hypothetical protein; InterPro IPR007256; KEGG: sta:STHERM_c18070 hypothetical protein; PFAM: Protein of unknown function DUF369; SPTR: Putative uncharacterized protein. (121 aa)    
Predicted Functional Partners:
AEJ60736.1
PFAM: Peptidase family M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: sta:STHERM_c18080 aminopeptidase; PFAM: Peptidase M28; SPTR: Peptidase M28.
       0.773
AEJ60735.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c18090 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
       0.552
AEJ60738.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: bur:Bcep18194_A4897 TetR family transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
       0.506
AEJ61270.1
PFAM: Protein of unknown function (DUF434); COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: sta:STHERM_c09730 hypothetical protein; PFAM: Protein of unknown function DUF434; SPTR: Putative uncharacterized protein.
  
     0.469
AEJ62413.1
PFAM: Radical SAM superfamily; B12 binding domain; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: sta:STHERM_c21130 methyltransferase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
  
     0.413
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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