STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60747.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (362 aa)    
Predicted Functional Partners:
AEJ60748.1
PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit; COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: sta:STHERM_c04470 riboflavin synthase alpha chain; PFAM: Lumazine-binding protein; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein.
  
 0.999
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.995
AEJ61658.1
PFAM: FlaG protein; InterPro IPR005186; KEGG: sta:STHERM_c07720 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein.
   
   0.806
AEJ61261.1
ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG0439 Biotin carboxylase; InterPro IPR003806; KEGG: sta:STHERM_c09640 CarB family protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein.
   
   0.789
AEJ60742.1
PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterPro IPR011538; KEGG: sta:STHERM_c04410 transporter; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit.
       0.768
AEJ60743.1
Hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
       0.767
AEJ60745.1
PFAM: Rnf-Nqr subunit, membrane protein; COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; KEGG: sta:STHERM_c04440 hypothetical protein; SPTR: Electron transport complex RsxE subunit; Belongs to the NqrDE/RnfAE family.
       0.767
AEJ60746.1
PFAM: Rnf-Nqr subunit, membrane protein; KEGG: sta:STHERM_c04450 hypothetical protein; SPTR: Electron transport complex protein RnfA.
       0.767
AEJ60741.1
KEGG: sta:STHERM_c04400 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.762
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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