STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60748.1PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit; COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: sta:STHERM_c04470 riboflavin synthase alpha chain; PFAM: Lumazine-binding protein; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein. (213 aa)    
Predicted Functional Partners:
AEJ60747.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
ribBA
GTP cyclohydrolase-2; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
AEJ61416.1
Cytidyltransferase-related domain protein; PFAM: FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR004821; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related.
  
 
 0.928
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
    0.918
rpmE2
PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31; COGs: COG0254 Ribosomal protein L31; HAMAP: 50S ribosomal protein L31; InterPro IPR002150; KEGG: sta:STHERM_c19880 50S ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31 type B; TIGRFAM: Ribosomal protein L31.
   
    0.696
AEJ60742.1
PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterPro IPR011538; KEGG: sta:STHERM_c04410 transporter; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit.
       0.688
AEJ60741.1
KEGG: sta:STHERM_c04400 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.683
AEJ60743.1
Hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
       0.683
AEJ60744.1
KEGG: sta:STHERM_c04430 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.683
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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