STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60753.1PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: ssm:Spirs_1025 transcriptional regulator, DeoR family; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family. (275 aa)    
Predicted Functional Partners:
AEJ62080.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: sta:STHERM_c17500 sugar kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
 
  
 0.913
AEJ62536.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c22360 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.859
AEJ60626.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: DNA binding domain, excisionase family; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR010093:IPR002178; KEGG: sta:STHERM_c03730 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: Excisionase/Xis, DNA-binding.
 
  
 0.553
AEJ60754.1
MULE transposase, conserved domain-containing protein; Required for the transposition of the insertion element.
       0.497
AEJ60627.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c03740 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.496
AEJ60751.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
    0.443
AEJ62292.1
PFAM: PTS system sugar-specific permease component; COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR004703; KEGG: sta:STHERM_c19850 hypothetical protein; PFAM: Phosphotransferase system, galactitol-specific IIC component; SPTR: PTS system Galactitol-specific IIC component.
 
  
 0.442
purC
PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636; KEGG: sta:STHERM_c04510 phosphoribosylaminoimidazole-succinocarboxamidesynthase; PFAM: SAICAR synthetase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase.
       0.435
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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